Publications

Selected Preprints from bioRxiv:

2023

A versatile synaptotagmin-1 nanobody provides perturbation-free live synaptic imaging and low linkage-error in super-resolution microscopy.
Villa Real KQZ*, Mougios N*, Rehm R*, Sograte-Idrissi S*, Albert L, Rahimi AM, Maidorn M, Hentze J, Martinez-Carranza M, Hosseini H, Saal KA, Oleksiievets N, Prigge M, Tsukanov R, Stenmark P#, Fornasiero EF#, Opazo F#.
bioRxiv
DOI: 10.1101/2023.01.30.525828

Selected Publications from PUBMED:

2023

The PPAR-γ agonist pioglitazone modulates proliferation and migration in HUVEC, HAOSMC and Human Arteriovenous Fistula-Derived Cells.
Ciavarella C, Motta I, Vasuri F, Palumbo T, Lisi AP, Costa A, Astolfi A, Valente S, Versura P, Fornasiero EF, Mauro R, Gargiulo M, Pasquinelli G.
International Journal of Molecular Sciences
DOI: 10.3390/ijms24054424

2022

Toward a hypothesis-free understanding of how phosphorylation dynamically impacts protein turnover.
Li W*, Salovska B*, Fornasiero EF, Liu Y#.
Proteomics. Proteomics and Systems Biology
DOI: 10.1002/pmic.202100387

Determining and interpreting protein lifetimes in mammalian tissues.
Fornasiero EF# and Savas JN#.
Trends in Biochemical Sciences
DOI: 10.1016/j.tibs.2022.08.011

IGF-1 receptor regulates upward firing rate homeostasis via the mitochondrial calcium uniporter.
Katsenelson M, Shapira I, Abbas E, Jevdokimenko K, Styr B, Ruggiero A, Aïd S, Fornasiero EF, Holzenberger M, Rizzoli SO, Slutsky I#.
Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.2121040119

Protein lifetimes in aged brains reveal a proteostatic adaptation linking physiological aging to neurodegeneration.
Kluever V#, Russo B, Mandad S, Kumar NH, Alevra M, Ori A, Rizzoli SO, Urlaub H, Schneider A#, Fornasiero EF#.
Science Advances
DOI: 10.1126/sciadv.abn4437

A reliable approach for revealing molecular targets in secondary ion mass spectrometry.
Li F#, Fornasiero EF, Dankovich TM, Kluever V, Rizzoli SO#.
International Journal of Molecular Sciences
DOI: 10.3390/ijms23094615

Centrosome-dependent microtubule modifications set the conditions for axon formation.
Meka DP, Kobler O, Hong S, Friedrich CM, Wuesthoff S, Henis M, Schwanke B, Krisp C, Schmuelling N, Rueter R, Ruecker T, Betleja E, Cheng T, Mahjoub MR, Soba P, Schlüter H, Fornasiero EF, Calderon de Anda F#.
Cell Reports
DOI: 10.1016/j.celrep.2022.110686

2021

Principles of brain aging: Status and challenges of modeling human molecular changes in mice.
Kluever V#, Fornasiero EF#.
Ageing Research Reviews
DOI: 10.1016/j.arr.2021.101465

Influence of subcellular localization and functional state on protein turnover.
Yousefi R*, Jevdokimenko K*, Kluever V, Pacheu-Grau D, Fornasiero EF#.
Cells
DOI: 10.3390/cells10071747

Brain long noncoding RNAs: multitask regulators of neuronal differentiation and function.
Keihani S, Kluever V, Fornasiero EF#.
Molecules
DOI: 10.3390/molecules26133951

Monitoring mitochondrial translation in living cells.
Yousefi R, Fornasiero EF, Cyganek L, Montoya J, Jakobs S, Rizzoli SO#, Rehling P#, Pacheu-Grau D.
EMBO Reports
DOI: 10.15252/embr.202051635

Protein phosphorylation in depolarized synaptosomes: dissecting primary effects of calcium from synaptic vesicle cycling.
Silbern I, Pan KT, Fiosins M, Bonn S, Rizzoli SO, Fornasiero EF#, Urlaub H#, Jahn R#.
Molecular & Cellular Proteomics
DOI: 10.1016/j.mcpro.2021.100061

NanoSIMS observations of mouse retinal cells reveal strict metabolic controls on nitrogen turnover.
Bonnin EA#, Fornasiero EF, Lange F, Turck CW, Rizzoli SO.
BMC Molecular and Cell Biology
DOI: 10.1186/s12860-020-00339-1

In vivo protein lifetime measurements across multiple organs in the zebrafish.
Mandad S, Kracht G, Fornasiero EF#.
Methods in Molecular Biology
DOI: 10.1007/978-1-0716-0970-5_23

Global and site-specific effect of phosphorylation on protein turnover.
Wu C, Ba Q, Lu D, Li W, Salovska B, Hou P, Mueller T, Rosenberger G, Gao E, Di Y, Zhou H, Fornasiero EF, Liu Y#.
Developmental Cell
DOI: 10.1016/j.devcel.2020.10.025

2020

A comparative analysis of the mobility of 45 proteins in the synaptic bouton.
Reshetniak S, Ußling JE, Perego E, Rammner B, Schikorski T, Fornasiero EF, Truckenbrodt S, Köster S, Rizzoli SO#.
The EMBO Journal
DOI: 10.15252/embj.2020104596

2019

The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43.
Keihani S, Kluever V, Mandad S, Bansal V, Rahman R, Fritsch E, Caldi Gomes L, Gärtner A, Kügler S, Urlaub H, Wren JD, Bonn S, Rizzoli SO, Fornasiero EF#.
Science Advances
DOI: advances.sciencemag.org/content/5/12/eaay2670

A mass spectrometry workflow for measuring protein turnover rates in vivo.
Alevra M, Mandad S, Ischebeck T, Urlaub H, Rizzoli SO#, Fornasiero EF#.
Nature Protocols
DOI: www.nature.com/articles/s41596-019-0222-y

Pathological changes are associated with shifts in the employment of synonymous codons at the transcriptome level.
Fornasiero EF#, Rizzoli SO#.
BMC Genomics
DOI: rdcu.be/bJAdb

2018

The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain.
Mandad S, Rahman RU, Centeno TP, Vidal RO, Wildhagen H, Rammner B, Keihani S, Opazo F, Urban I, Ischebeck T, Kirli K, Benito E, Fischer A, Yousefi RY, Dennerlein S, Rehling P, Feussner I, Urlaub H, Bonn S#, Rizzoli SO#, Fornasiero EF#.
Sci Rep. 2018 Nov 15;8(1):16913.
DOI: 10.1038/s41598-018-35277-8

Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions.
Fornasiero EF*,#, Mandad S, Wildhagen H, Alevra M, Rammner B, Keihani S, Opazo F, Urban I, Ischebeck T, Sakib MS, Fard MK, Kirli K, Centeno TP, Vidal RO, Rahman RU, Benito E, Fischer A, Dennerlein S, Rehling P, Feussner I, Bonn S, Simons M, Urlaub H#, Rizzoli SO#.

Nat Commun. 2018 Oct 12;9(1):4230.

DOI: 10.1038/s41467-018-06519-0

Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission.
Truckenbrodt S#, Viplav A, Jähne S, Vogts A, Denker A, Wildhagen H, Fornasiero EF#, Rizzoli SO#.
EMBO J. 2018 Aug 1;37(15)
DOI: 10.15252/embj.201798044

2017

BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions.
Fard MK#, van der Meer F, Sánchez P, Cantuti-Castelvetri L, Mandad S, Jäkel S, Fornasiero EF, Schmitt S, Ehrlich M, Starost L, Kuhlmann T, Sergiou C, Schultz V, Wrzos C, Brück W, Urlaub H, Dimou L, Stadelmann C#, Simons M#.
M. Sci Transl Med. 2017 Dec 6;9(419).
DOI: 10.1126/scitranslmed.aam7816

2015

Super-resolution imaging for cell biologists: concepts, applications, current challenges and developments.
Fornasiero EF#, Opazo F#.
Bioessays. 2015 Apr;37(4):436-51. Review.
DOI: 10.1002/bies.20140017

Here you find the complete list of publications

Book chapter contribution:
Cellular and Molecular Applications of Superresolution Microscopy.
Fornasiero EF and Opazo LF.
In the book “Fluorescence Microscopy” from Cornea and Conn.
DOI: 10.1016/B978-0-12-409513-7.00010-5

Book editing:
Super-Resolution Microscopy Techniques in the Neurosciences.
Fornasiero EF, Rizzoli SO.
Springer Neuromethods, Humana Press February 2014.
DOI: 10.1007/978-1-62703-983-3